10X Methylation Genetic Test

At-home DNA test kit + Personalized health reports
Discover how your genetics influence methylation, a key process involved in how your body converts and uses essential nutrients that support energy, detoxification, and overall wellness.

Personalized genetic report with clinically relevant insights you can use to guide next steps
Simple at-home saliva collection with no blood and no lab visits
Digital reports designed to be easy to understand and act on

$599.00

Science You Can Trust

Backed by 10X medical experts

CLIA Certified

100% private data

Get Your Personalized Methylation Genetic Report

Your genetic report helps you understand:

  • How your genetics may influence methylation, a key process involved in nutrient absorption
  • Genetic factors that can affect how your body processes B vitamins and other essential nutrients
  • Variations that may impact energy production, detoxification, and cellular function
  • How multiple genetic variations work together to influence methylation rather than viewing results in isolation
  • Which methylation-related factors may be more or less impactful for you based on your genetic profile

Your Methylation Genetic Test includes:

  • One focused genetic report centered on methylation pathways
  • Analysis of genetic variations involved in nutrient and vitamin conversion
  • Clinically relevant insights related to energy production and recovery
  • Clear explanations designed to help you understand your results without technical overwhelm
  • Optional personalized recommendations available after you review your report

Each 10X Health Methylation Genetic Test Includes

Precision DNA Test Kit

Includes your saliva collection tube, step-by-step instructions, and prepaid return envelope.

Comprehensive Genetic Report

Analyzes genetic variations involved in methylation to help explain how your body converts and uses essential nutrients.

Each 10X Health Methylation Genetic Test Includes

Precision DNA Test Kit

Includes your saliva collection tube, step-by-step instructions, and prepaid return envelope.

Comprehensive Genetic Report

Analyzes genetic variations involved in methylation to help explain how your body converts and uses essential nutrients.

Grant Cardone

"I was in daily chronic pain and now, at 64, I am in the best shape of my life. I am free of pain, anxiety, stress, and I am able to accomplish more than any other time in my life."

Grant Cardone

"I was in daily chronic pain and now, at 64, I am in the best shape of my life. I am free of pain, anxiety, stress, and I am able to accomplish more than any other time in my life."

Find What Holds You Back and Fix it at the Source

Learn how certain genetic variations may impact key methylation processes.

*The gene icons shown here are for illustrative purposes only. Your actual report will display results using a color-coded system: green indicates no variant, yellow indicates a variant inherited from one parent, and red indicates variants inherited from both parents.

MTHFR GENE

Converts folate into an active form that supports DNA repair and detoxification.

Variations in the MTHFR gene may influence your ability to process folate efficiently, leading to fatigue and slower recovery.

MTR GENE

Works with MTHFR to convert homocysteine into methionine an essential process for DNA synthesis

Variations in the MTR gene may influence your ability to recycle to recycle B12 efficiently, leading to fatigue and higher homocysteine levels.

MTRR GENE

Regenerates Vitamin B12 for smooth methylation, essential for DNA repair and energy.

Variations in the MTRR gene may affect your ability to recycle B12, which can contribute to low energy, reduced stress resilience, and slower recovery.

AHCY GENE

Converts folate into an active form that supports DNA repair and detoxification.

Variations in the AHCY gene may disrupt methylation efficiency, which can impact energy levels, cognitive clarity, and overall metabolic balance.

COMT GENE

Converts folate into an active form that supports DNA repair and detoxification.

Variations in the COMT gene may influence how you respond to stress, potentially leading to mood changes, mental fatigue, or feeling overstimulated.

Focused Genetic Insights Designed for Action

This report helps explain how genetic differences related to methylation can influence nutrient conversion, energy levels, and cellular support. The insights give you a clearer understanding of what matters most and how to approach next steps.

5

KEY GENES

The 10X Genetic Methylation Test analyzes five key genes, including MTHFR

44%

POPULATION

Carry a MTHFR genetic mutation linked to health. Understanding it offers insights into future risks.

5

KEY GENES

The 10X Genetic Methylation Test analyzes five key genes, including MTHFR

44%

POPULATION

Carry a MTHFR genetic mutation linked to health. Understanding it offers insights into future risks.

The Test is Quick and Your Data is Safe

Person holding a white device with QR code and text on a blurred background

ORDER YOUR KIT

We'll ship a simple at-home DNA test straight to your door.

COLLECT YOUR SAMPLE

Follow the easy instructions to collect your saliva sample and send your sample back—no lab visit needed!

GET YOUR RESULTS

In 2–3 weeks, you’ll get your personalized health report and recommendations based on your genetics.

160,000+

Genetic tests analyzed and
counting

160,000+

Genetic tests analyzed and
counting

Find The Right Test for You

Precision vs Methylation Genetic Test

Methylation Test

$599.00

Precision Genetic Test

$1299.00

View Details

Expanded genetic analysis

Expanded genetic analysis

COMT, AHCY, MTR, MTRR, MTHFR gene analysis

COMT, AHCY, MTR, MTRR, MTHFR gene analysis

Methylation

Methylation

Supplement protocol

Supplement protocol

Weight loss & precision supplement protocol

Weight loss & precision supplement protocol

Access to precision IV therapy (where available)

Access to precision IV therapy (where available)

Nutrition + weight Loss +workout plan

Nutrition + weight Loss +workout plan

Nutrition & weight loss report

Nutrition & weight loss report

Personalized food guidance

Personalized food guidance

Precision IV QR

Precision IV QR

Professional consult call available

Professional consult call available

Your privacy protected

Your privacy protected

Find The Right Test for You

Precision vs Methylation Genetic Test

Methylation Test

$599.00

Precision Genetic Test

$1299.00

View Details

Expanded genetic analysis

COMT, AHCY, MTR, MTRR, MTHFR gene analysis

Methylation

Supplement protocol

Weight loss & precision supplement protocol

Access to precision IV therapy (where available)

Nutrition + weight Loss +workout plan

Nutrition & weight loss report

Personalized food guidance

Precision IV QR

Professional consult call available

Your privacy protected

*This genetic test is intended to identify specific genetic mutations. Some individuals, but not all, may experience symptoms associated with these genetic breaks. This product is not intended to diagnose, treat, cure, or prevent any disease.

FAQs

Answers to the most common questions about 10X Health Methylation Genetic Test

The 10X Methylation Genetic Test analyzes the five key genes (MTHFR, MTR, MTRR, AHCY, COMT) involved in your body's methylation cycle. The methylation cycle is the body’s process of converting raw materials into usable nutrients (think about how we can get protein from a piece of chicken). By pinpointing the disruptions in this pathway, we can recommend the specific nutrients your body needs to function optimally. As your genes never change, this is a once-in-a-lifetime test! 

Results typically take up to two weeks once your sample is received at the lab. As soon as your report is ready, we’ll send an email notification to log in and view them in your My Wellness Portal. 

The Methylation Genetic Test report is designed to be self-guided with videos and explanations throughout, but if you have additional questions, we offer the opportunity to schedule a personalized 1:1 consultation with one of our 10X Clinical Providers.  To schedule this call, please view your results on MyWellness Portal and click on the Clarity Call tile at the top of the page.   

Your MGT report will provide supplement recommendations based on your unique genetic profile, specifically related to your methylation cycle. All supplement recommendations are available for purchase within your report. Always consult with your healthcare provider prior to taking new supplements if you are pregnant, nursing or have any medical conditions.  

Please contact Support for assistance at (844) 977-2810 or support@10xhealthsystem.com.

What’s Inside Your Genetic Methylation Report:

Your report is a step-by-step roadmap that explains what your results mean and how to act on them to create the improvements you're after.

Clear Variant Breakdown

You’ll see whether each gene shows 0, 1, or 2 variants, what that means for enzyme activity, and how that may influence how your body processes nutrients and supports energy production.

Personalized Genomic Commentary

Each gene includes a plain-English explanation of:

  • Affected body systems
  • Common symptom patterns
  • How enzyme activity may be functioning
  • What that could mean for your daily experience

Custom Supplement Protocol

You receive a structured supplement plan designed around your results, including:

  • Exact nutrients recommended
  • Preferred forms of key vitamins (such as specific B12 and folate forms)
  • Weight-based dosage guidance
  • Important cautions to avoid over-methylation
  • The option to purchase these exact supplements in their recommended dosages from our shop (this is an optional, extra charge)

Nutrient Application Guidance

Your report connects each gene to the nutrients that support its function and explains why they matter for your methylation pathway.

Food and Lifestyle Recommendations

You’ll also receive:

  • Targeted food lists rich in methylation-support nutrients
  • Lifestyle strategies to reduce stress on the pathway
  • Sleep, hydration, movement, and environmental guidance

Methylation Pathway Overview

A visual map helps you understand how your genes interact and how one variant can influence the rest of the pathway.