NewMethylation+ Genetic Test

The Methylation Analysis That Comes With a Plan And Human Guidance

Tired, foggy, not sleeping, not losing weight, or just off when your labs come back fine? The new Methylation+ Genetic Test reads 27 genes across 6 connected body systems and turns what it finds into a plan built for the genes you actually have.

27 Genes6 Connected SystemsOne Plan
$599.00Free Wellness Consultation Included

One-time test, lifetime value: your DNA never changes · HSA/FSA eligible

Each 10X Health Methylation Genetic Test Includes

Precision DNA Test Kit

Precision DNA Test Kit

Saliva collection tube, step-by-step instructions, and a prepaid return envelope.

Comprehensive Genetic Report

Comprehensive Genetic Report

Analyzes 27 genes across 6 connected body systems to explain how your body uses nutrients.

Wellness Consultation

Wellness Consultation

A one-on-one call with a 10X team member to walk you through your results.

Recommended Supplement Protocol

Recommended Supplement Protocol

A personalized supplement and nutrition protocol matched to your genetics.

CLIACertified lab
160K+Tests analyzed
10XMedical Expert Approved

Real results

What people are saying

★★★★★
“IT WORKS! I did the genetic test and received my supplements according to the results. I started feeling the positive effects within three days of taking them. I am 68 years old and feel like I'm in my thirties.”
★★★★★
“Since we have converted to the 10X products life has improved tremendously. The genetic test showed the map to our specific needs and from there you begin to see healing like never before. Start with the genetic test from 10x first and save yourself some time and money by skipping the guesswork….guessing what your body needs is a shot in the dark….get to the real stuff by checking your genetic data.”
★★★★★
“I changed two months ago to use 10X based on my genetic test results and I feel great. Very good quality products and I love how they give you a specific set of supplements to take and they also tell you which ones not to take due to your genetic variance. Great stuff and I love it.”
★★★★★
“Supplements are great and the genetic testing is a wealth of knowledge for a healthier life. Knowing where the breakdowns are and how to help them is crucial.”
★★★★★
“Pleasantly surprised about the whole process.... Couldn't be more happy. The information I receive it was great. Im already down 14 pounds. I would highly recommend during the genetic test and the blood work.”

Methylation Genetic Test · 2-minute check

Find out if the Methylation Genetic Test is right for you

Start with what you feel. We'll walk you through six common symptoms. For each one you say yes to, we'll show the genes that could be involved. No sign-up. Nothing saved.

This product is not intended to diagnose, treat, cure, or prevent any disease.

Common signs of nutrient gaps

Start with what you feel

When your body can't use nutrients efficiently, the signs show up in daily life, even with a clean diet and solid habits. The pattern often traces back to your genes.

Genes
Brain fog
Brain fog
Genes we read
COMT rs4680
Dopamine & stress-hormone clearance
MTHFR rs1801133
Folate → active methyl-folate
MTR rs1805087
B12-dependent methylation
Part of your 27-gene report
Genes
Fatigue
Fatigue
Genes we read
MTHFR rs1801133
Folate activation for energy
MTRR rs1801394
Vitamin B12 recycling
SOD2 rs4880
Mitochondrial oxidative defense
Part of your 27-gene report
Genes
Poor sleep
Poor sleep
Genes we read
COMT rs4680
Catecholamine wind-down
TPH2 rs4570625
Serotonin → melatonin pathway
VDR rs1544410
Vitamin D & sleep regulation
Part of your 27-gene report
Genes
Anxious mood
Anxious mood
Genes we read
COMT rs4680
Stress resilience & mood
MTHFR rs1801131
Methyl-folate output
TPH2 rs4570625
Serotonin synthesis
Part of your 27-gene report
Genes
Can't lose weight
Can't lose weight
Genes we read
VDR rs1544410
Vitamin D & metabolic signaling
MTHFR rs1801133
Methylation drive & metabolism
AHCY rs819147
SAMe / SAH balance
Part of your 27-gene report
Genes
Low focus
Low focus
Genes we read
COMT rs4680
Prefrontal dopamine tone
TH rs10770141
Dopamine production
MTR rs1805087
Methionine synthesis
Part of your 27-gene report

Now analyzes 27 genes

27 genes · 6 connected body systems

Find what holds you back so you can fix it at the source

Tap a point on the body to see the connected system, what your genes may be affecting, and what to do about it.

Interactive body-system map from your methylation reportInteractive body-system map from your methylation report

Select a point on the body to explore

System 1 of 6

Mood, Focus & StressNew

How your body manages neurotransmitters like dopamine and serotonin, which may support mood, focus, stress resilience, and sleep.

THDDC/AADCCOMTTPH1TPH2

System 2 of 6

Heart & Brain

How your body manages homocysteine, which may support cardiovascular health, cognitive aging, and long-term brain protection.

MTRMTRRBHMTMATAHCY

System 3 of 6

Bone, Immune & Hormone HealthNew

How your body produces, activates, and uses vitamin D, which may support bone strength, immune function, mood, and a healthy inflammatory response.

VDRCYP2R1CYP27B1CYP24A1DHCR7GC

System 4 of 6

Detox & Cellular HealthNew

Your master detox system: how your body uses glutathione to neutralize toxins, heavy metals, and everyday environmental exposures.

CTHGSTM1GSTP1GSTT1

System 5 of 6

Vascular & Oxidative HealthNew

How your body manages oxidative stress and nitric oxide, which may support circulation, healthy blood pressure, and cellular protection.

SOD2GPX1ACE

System 6 of 6

Energy & Absorption

How your body activates folate (folic acid) to power your methylation cycle, energy production, and nutrient absorption.

MTHFRMTHFD1SLC19A1FUT2

Genetic variants represent tendencies and predispositions, not diagnoses or direct measurements of enzyme activity. Your report frames results as insights to guide next steps.

Why 10X

Built on clinical credibility

Clinical credibility

Clinical credibility

Processed in CLIA-certified labs and reviewed by 10X medical experts, the same standard trusted by clinicians.

Digital precision

Digital precision

Your results translate directly into a personalized supplement and nutrition protocol matched to your genetics.

Human guidance

Human guidance

A Wellness Consultation walks you through your results so you know exactly what to do next.

Your data stays yours

Your DNA is not the product.

We don't sell your genetic information. Not to pharma. Not to researchers. Not to anyone. The price of the test is the price.

Never sold
Never shared
Yours to delete

The test is quick. Your data is safe.

160,000+
genetic tests analyzed and counting
STEP 1

Order your kit

We ship a simple at-home DNA test straight to your door.

STEP 2

Collect your sample

Follow the easy instructions to collect your saliva and mail it back, no lab visit needed.

STEP 3

Get your plan

Review your personalized 27-gene report, then book your free Wellness Consultation.

Find the right test for you

Start with methylation. Upgrade to the full precision system whenever you're ready.

 
Methylation
$599
Precision
$1,299
Genes analyzed
27
50+
Body systems
6 connected body systems
8 body systems + plan
Personalized report
3 reports (490+ pp)
DNA-driven supplement protocol
Custom-formulated
Nutrition & weight plan
Precision IV protocol
Free Wellness Consultation
Your DNA is never sold
 

FAQs

What is the 10X Methylation Genetic Test?

It analyzes 27 genes across 6 connected body systems involved in how your body converts raw materials into usable nutrients: your methylation, vitamin D, glutathione, free-radical, and neurotransmitter systems. By pinpointing where your genes may slow a system down, we can recommend the specific nutrients and steps your body needs. Your genes never change, so this is a once-in-a-lifetime test.

Is my genetic data private?

Yes. We don't sell your genetic information. Not to pharma companies, not to research firms, not to anyone. The price of the test is the price; your DNA is not the product, and your data is yours to delete.

How do I receive my results?

Results are typically ready within a few weeks of the lab receiving your sample. We'll email you to log in and view them in your My Wellness Portal.

Will it tell me what supplements I need?

Your report provides supplement and lifestyle recommendations tailored to your results, with embedded buy links. Recommendations may include single-ingredient supplements. Always consult your healthcare provider before starting new supplements.

What is the free Wellness Consultation?

Every test includes a complimentary call with a 10X team member who walks you through your report and helps you decide on next steps, with no pressure to buy anything.

10X Health’s Genetic tests offer insights into genetic predispositions; results are informational only, do not constitute medical advice, and do not guarantee outcomes. These products are not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare provider before making any health decisions based on your results. This page contains AI-generated images and do not depict real patients, customers, or actual results. Individual results may vary.